GLI2 anticorps

N° du produit ABIN8121651

L’anticorps anti-GLI2 Polyclonal Lapin est utilisé pour la détection de GLI2 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour GLI2 anticorps (ABIN8121651)

Antigène: GLI2 (GLI Family Zinc Finger 2 (GLI2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLI2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GLI2 anticorps

Fonction: GLI2 Antibody

Specificité: GLI2 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur GLI2

Antigène: GLI2 (GLI Family Zinc Finger 2 (GLI2))

Autre désignation: GLI2

Sujet:

Background: This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell.The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008],

Gene Name: GLI2 THP

Protein Name: Zinc finger protein GLI2 (Tax helper protein)

ID gène: 2736

UniProt: P10070

Pathways: Signalisation Hedgehog, Dopaminergic Neurogenesis