GSTM5 anticorps (AA 99-149)

N° du produit ABIN8121723

L’anticorps anti-GSTM5 Polyclonal Lapin est utilisé pour la détection de GSTM5 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour GSTM5 anticorps (AA 99-149) (ABIN8121723)

Antigène: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GSTM5 anticorps

Épitope: AA 99-149

Fonction: GSTM5 Antibody

Specificité: This antibody detects endogenous levels of GSTM5 at Human/Mouse/Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human GSTM5 AA range: 99-149

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur GSTM5

Antigène: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Autre désignation: GSTM5

Sujet:

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. [provided by RefSeq, Jul 2008],

Gene Name: GSTM5

Protein Name: GSTM5

ID gène: 2949

UniProt: P46439