Hexokinase 2 anticorps
Aperçu rapide pour Hexokinase 2 anticorps (ABIN8121949)
Antigène
Voir toutes Hexokinase 2 (HK2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Hexokinase II Rabbit mAb
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Specificité
- This antibody detects endogenous levels of Hexokinase II protein.
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Purification
- The antibody was purified by protein A affinity chromatography.
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Immunogène
- Recombinant protein (or fragment).
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Isotype
- IgG
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Indications d'application
- WB, 1:1000-1:5000 | IHC, 1:200-1:400 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at-20°C. Avoid freeze / thaw cycles.
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- Hexokinase 2 (HK2)
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Autre désignation
- Hexokinase II
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Sujet
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Synonyms: HK2, Hexokinase-2, Hexokinase type II, HK II, Muscle form hexokinase
Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009],
Gene Name: HK2
Protein Name: Hexokinase II
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ID gène
- 3099
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UniProt
- P52789
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Pathways
- Signalisation PI3K-Akt, Carbohydrate Homeostasis, L'effet Warburg
Antigène
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