IL21 Receptor anticorps

N° du produit ABIN8122334

Cet anticorps Lapin Polyclonal détecte spécifiquement IL21 Receptor dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour IL21 Receptor anticorps (ABIN8122334)

Antigène: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL21 Receptor est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-IL21 Receptor anticorps

Fonction: IL21R Antibody

Specificité: IL21R Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur IL21 Receptor

Antigène: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Autre désignation: IL21R

Sujet:

Background: The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010],

Gene Name: IL21R NILR UNQ3121/PRO10273

Protein Name: Interleukin-21 receptor (IL-21 receptor) (IL-21R) (Novel interleukin receptor) (CD antigen CD360)

ID gène: 50615

UniProt: Q9HBE5

Pathways: Signalistation JAK/STAT