MAPK7 anticorps
Aperçu rapide pour MAPK7 anticorps (ABIN8122995)
Antigène
Voir toutes MAPK7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- ERK 5 Antibody
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Specificité
- The antibody detects endogenous ERK 5 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Recombinant Protein of ERK 5
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Isotype
- IgG
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Indications d'application
- WB 1:1000-2000 IHC 1:200-500. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
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Autre désignation
- ERK 5
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Sujet
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Synonyms: MAPK7, BMK1, ERK5, PRKM7, Mitogen-activated protein kinase 7, MAP kinase 7, MAPK 7, Big MAP kinase 1, BMK-1, Extracellular signal-regulated kinase 5, ERK-5
Background: The protein encoded byThis gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
Gene Name: MAPK7,ERK5
Protein Name: Mitogen-activated protein kinase 7
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ID gène
- 5598
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UniProt
- Q13164
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Pathways
- Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling
Antigène
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