MYLK anticorps (pTyr471)

N° du produit ABIN8123150

Cet anticorps Lapin Polyclonal détecte spécifiquement MYLK dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MYLK anticorps (pTyr471) (ABIN8123150)

Antigène: MYLK (Myosin Light Chain Kinase (MYLK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYLK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-MYLK anticorps

Épitope: pTyr471

Fonction: MLCK (Phospho Tyr471) Antibody

Specificité: This antibody detects endogenous levels of Human,Mouse,Rat MLCK (Phospho Tyr471)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human MLCK (Phospho Tyr471)

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MYLK

Antigène: MYLK (Myosin Light Chain Kinase (MYLK))

Autre désignation: MLCK

Sujet:

Synonyms: Myosin light chain kinase, smooth muscle (MLCK; smMLCK; EC 2.7.11.18; Kinase-related protein; KRP; Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]

Background: myosin light chain kinase(MYLK) Homo sapiens This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity.This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been

Gene Name: MYLK MLCK MLCK1 MYLK1

Protein Name: MLCK (Phospho Tyr471)

ID gène: 4638

UniProt: Q15746