Nibrin anticorps (pSer343)

N° du produit ABIN8123328

L’anticorps anti-Nibrin Polyclonal Lapin est utilisé pour la détection de Nibrin dans des échantillons de Humain et Souris. Il a été validé pour WB.

Aperçu rapide pour Nibrin anticorps (pSer343) (ABIN8123328)

Antigène: Nibrin (NBN)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nibrin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Nibrin anticorps

Épitope: pSer343

Fonction: p95/NBS1 (Phospho Ser343) Antibody

Specificité: This antibody detects endogenous levels of Human Mouse p95 or NBS1 (phospho-Ser343)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized phosho peptide around human p95 (Ser343)

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Nibrin

Antigène: Nibrin (NBN)

Autre désignation: p95/NBS1

Sujet:

Synonyms: Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1)

Background: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008],

Gene Name: NBN NBS NBS1 P95

Protein Name: p95/NBS1 (Ser343)

ID gène: 4683

UniProt: O60934

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response