NAIP anticorps (AA 1191-1240)

N° du produit ABIN8123355

L’anticorps anti-NAIP Polyclonal Lapin est utilisé pour la détection de NAIP dans des échantillons de Humain et Souris. Il a été validé pour IHC, ELISA et IF.

Aperçu rapide pour NAIP anticorps (AA 1191-1240) (ABIN8123355)

Antigène: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAIP est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-NAIP anticorps

Épitope: AA 1191-1240

Fonction: NAIP Antibody

Specificité: The antibody detects endogenous NAIP

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthetic peptide from human protein at AA range: 1191-1240

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur NAIP

Antigène: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Autre désignation: NAIP

Sujet:

Synonyms: Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein)

Background: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length, additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1.The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by Ref

Gene Name: NAIP BIRC1

Protein Name: Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein)

ID gène: 4671

UniProt: Q13075

Pathways: Apoptose, Inflammasome