STAT4 anticorps (pTyr693)
Aperçu rapide pour STAT4 anticorps (pTyr693) (ABIN8124696)
Antigène
Voir toutes STAT4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr693
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Fonction
- Stat4 (phospho Tyr693) Antibody
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Specificité
- Phospho-Stat4 (Y693) Polyclonal Antibody detects endogenous levels of Stat4 protein only when phosphorylated at Y693.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized phospho-peptide around the phosphorylation site of human Stat4 (phospho Tyr693)
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
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Autre désignation
- Stat4
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Sujet
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Synonyms: STAT4, Signal transducer and activator of transcription 4
Background: The protein encoded byThis gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],
Gene Name: STAT4
Protein Name: Signal transducer and activator of transcription 4
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ID gène
- 6775
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UniProt
- Q14765
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Pathways
- Signalistation JAK/STAT
Antigène
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