TAPBP anticorps

N° du produit ABIN8125112

Cet anticorps Lapin Polyclonal détecte spécifiquement TAPBP dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour TAPBP anticorps (ABIN8125112)

Antigène: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAPBP est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TAPBP anticorps

Fonction: TPSN Antibody

Specificité: TPSN Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TAPBP

Antigène: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Autre désignation: TPSN

Sujet:

Background: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Gene Name: TAPBP NGS17 TAPA

Protein Name: Tapasin (TPN) (TPSN) (NGS-17) (TAP-associated protein) (TAP-binding protein)

ID gène: 6892

UniProt: O15533