TIGAR anticorps

N° du produit ABIN8125254

L’anticorps anti-TIGAR Polyclonal Lapin est utilisé pour la détection de TIGAR dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour TIGAR anticorps (ABIN8125254)

Antigène: TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIGAR est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TIGAR anticorps

Fonction: TIGAR Antibody

Specificité: TIGAR Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TIGAR

Antigène: TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))

Autre désignation: TIGAR

Sujet:

Background: This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq, Jul 2008],

Gene Name: TIGAR C12orf5

Protein Name: Fructose-2,6-bisphosphatase TIGAR (EC 3.1.3.46) (TP53-induced glycolysis and apoptosis regulator)

ID gène: 57103

UniProt: Q9NQ88

Pathways: L'effet Warburg