VASP anticorps (pSer239)
Aperçu rapide pour VASP anticorps (pSer239) (ABIN8125681)
Antigène
Voir toutes VASP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer239
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Fonction
- VASP (Phospho Ser239) Antibody
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Specificité
- This antibody detects endogenous levels of Human Mouse Rat VASP (phospho-Ser239)
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Immunogène
- Synthesized phosho peptide around human VASP (Ser239)
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Isotype
- IgG
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Indications d'application
- WB 1:1000-2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
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Autre désignation
- VASP
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Sujet
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Synonyms: Vasodilator-stimulated phosphoprotein (VASP)
Background: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008],
Gene Name: VASP
Protein Name: VASP (Ser239)
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ID gène
- 7408
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UniProt
- P50552
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Pathways
- TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
Antigène
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