Nicastrin anticorps (PE)
Aperçu rapide pour Nicastrin anticorps (PE) (ABIN761811)
Antigène
Voir toutes Nicastrin (NCSTN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Souris
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Homologie
- Human,Rat,Cow,Pig,Horse,Chicken
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human Nicastrin
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- Nicastrin (NCSTN)
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Autre désignation
- Nicastrin
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Sujet
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Synonyms: ATAG1874, Nicastrin, NCSTN, KIAA0253, UNQ1874/PRO4317
Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
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Poids moléculaire
- 85kDa
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ID gène
- 23385
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UniProt
- Q92542
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Pathways
- Signalisation Notch, Neurotrophin Signaling Pathway
Antigène
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