SOCS3 anticorps

N° du produit ABIN781166

Cet anticorps Souris Monoclonal détecte spécifiquement SOCS3 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SOCS3 anticorps (ABIN781166)

Antigène: SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SOCS3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SOCS3 anticorps

Purification: Protein G-Sepharose affinity purified.

Immunogène: Recombinant fragment of Human SOCS3 (N-terminus).

Isotype: IgG

Information d'application

Indications d'application: Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 50µg/50µl

Buffer: 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur SOCS3

Antigène: SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

Autre désignation: SOCS3

Sujet: SOCS3 is an SH2-containing protein that binds to the activation loop of Janus kinases, inhibiting kinase activity and thereby suppressing cytokine signaling. It is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. The expression of the SOCS3 gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. Studies of the mouse counterpart of the SOCS3 gene suggested this gene is involved in the negative regulation of fetal liver hematopoiesis, and placental development.

Poids moléculaire: 45kDa

NCBI Accession: NM_003955

Pathways: Signalistation JAK/STAT, Response to Growth Hormone Stimulus, Hepatitis C