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CD28 anticorps

CD28 Reactivité: Humain, Primate FACS, WB, IF, IP, Func, IHC (fro) Hôte: Souris Monoclonal CD28-2 unconjugated
N° du produit ABIN781619
  • Antigène Voir toutes CD28 Anticorps
    CD28
    Reactivité
    • 180
    • 129
    • 60
    • 38
    • 21
    • 20
    • 12
    • 12
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Primate
    Hôte
    • 142
    • 78
    • 28
    • 18
    • 8
    • 3
    • 2
    Souris
    Clonalité
    • 199
    • 74
    • 3
    Monoclonal
    Conjugué
    • 92
    • 30
    • 28
    • 20
    • 15
    • 7
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    • 6
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    • 4
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    • 3
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    • 3
    • 3
    • 3
    • 3
    • 3
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    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD28 est non-conjugé
    Application
    • 203
    • 93
    • 49
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    • 39
    • 30
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    • 26
    • 20
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    • 13
    • 7
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    Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    This antibody reacts with CD28, a disulfide-linked homodimeric type I glycoprotein (monomer of Mw 44 kDa) which is a critical costimulatory receptor of T cells.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, Non-Human Primates
    Purification
    Protein A affinity chromatography
    Pureté
    > 95 % (by SDS-PAGE)
    Clone
    CD28-2
    Isotype
    IgG1
    Top Product
    Discover our top product CD28 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Antigène
    CD28
    Autre désignation
    CD28 (CD28 Produits)
    Synonymes
    anticorps Tp44, anticorps CD28RNA, anticorps cd28, anticorps CD28 molecule, anticorps CD28 antigen, anticorps Cd28 molecule, anticorps CD28 molecule L homeolog, anticorps CD28, anticorps Cd28, anticorps cd28.L
    Sujet
    CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.Synonyms: T-cell-specific surface glycoprotein CD28, TP44
    ID gène
    940
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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