ROCK2 anticorps (Center)
Aperçu rapide pour ROCK2 anticorps (Center) (ABIN783448)
Antigène
Voir toutes ROCK2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Specificité
- This antibody detects ROCK2 at Center. Three isoforms of ROCK2 are known to exist, this antibody recognizes all three isoforms. ROCK2 antibody is predicted to not cross-react with other ROCK protein family members.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 15 amino acid peptide near the center of human ROC
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))
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Autre désignation
- ROCK2
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Sujet
- ROCK2 is a member of the AGC serine/threonine protein kinase family that regulates the assembly of the actin cytoskeleton. ROCK2 contains a protein kinase domain, a coiled-coil region and a zinc finger region and appears to be present as a dimer. ROCK2, like its isozyme ROCK1, is a downstream target of the small G-protein Rho and plays a role in smooth muscle contraction, malignant cell transformation, tumor invasion and metastasis, and mediates the cellular morphological changes during apoptosis.Synonyms: KIAA0619, ROCK-2, Rho kinase 2, Rho-associated, Rho-associated protein kinase 2, coiled-coil-containing protein kinase 2, p164ROCK-2
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ID gène
- 9475
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NCBI Accession
- NP_004841
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UniProt
- O75116
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Pathways
- Dynamique des Microtubules, Signalisation WNT, Tube Formation
Antigène
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