ROCK2 anticorps (Center)

N° du produit ABIN783448

Détail du produit anti-ROCK2 anticorps

Antigène: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ROCK2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects ROCK2 at Center. Three isoforms of ROCK2 are known to exist, this antibody recognizes all three isoforms. ROCK2 antibody is predicted to not cross-react with other ROCK protein family members.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide near the center of human ROC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur ROCK2

Antigène: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Autre désignation: ROCK2 (ROCK2 Produits)

Synonymes: anticorps rocka-a, anticorps xROK, anticorps rock2, anticorps rok2, anticorps ROCK2, anticorps B230113H15Rik, anticorps ROKalpha, anticorps Rho-kinase, anticorps Rock-II, anticorps Rock2m, anticorps mKIAA0619, anticorps ROCK-II, anticorps ROK, anticorps Rho-associated, coiled-coil containing protein kinase 2 L homeolog, anticorps rho-associated, coiled-coil containing protein kinase 2a, anticorps Rho associated coiled-coil containing protein kinase 2, anticorps Rho-associated, coiled-coil containing protein kinase 2, anticorps Rho-associated coiled-coil containing protein kinase 2, anticorps rock2.L, anticorps rock2a, anticorps ROCK2, anticorps Rock2

Sujet: ROCK2 is a member of the AGC serine/threonine protein kinase family that regulates the assembly of the actin cytoskeleton. ROCK2 contains a protein kinase domain, a coiled-coil region and a zinc finger region and appears to be present as a dimer. ROCK2, like its isozyme ROCK1, is a downstream target of the small G-protein Rho and plays a role in smooth muscle contraction, malignant cell transformation, tumor invasion and metastasis, and mediates the cellular morphological changes during apoptosis.Synonyms: KIAA0619, ROCK-2, Rho kinase 2, Rho-associated, Rho-associated protein kinase 2, coiled-coil-containing protein kinase 2, p164ROCK-2

ID gène: 9475

NCBI Accession: NP_004841

UniProt: O75116

Pathways: Dynamique des Microtubules, Signalisation WNT, Tube Formation