SIK1 anticorps (Center)

N° du produit ABIN783464

L’anticorps Lapin Polyclonal anti-SIK1 a été validé pour WB et EIA. Il convient pour détecter SIK1 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour SIK1 anticorps (Center) (ABIN783464)

Antigène: SIK1 (Salt-Inducible Kinase 1 (SIK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIK1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-SIK1 anticorps

Épitope: Center

Specificité: This antibody detects SIK1 at Center. Two isoforms of SIK1 are known to exist, this antibody will detect both isoforms. SIK1 antibody is predicted to not cross-react with other SIK protein family members.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid peptide near the center of human SIK1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-SIK1 (ABIN783464)

Chen, Shen, Wu, Hua, Kuang, Li, Peng: "CISD2 associated with proliferation indicates negative prognosis in patients with hepatocellular carcinoma." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 10, pp. 13725-38, (2016) (PubMed).

Détails sur SIK1

Antigène: SIK1 (Salt-Inducible Kinase 1 (SIK1))

Autre désignation: SIK1

Sujet: Salt-inducible kinase 1 (SIK1), also known as SNF1LK or MSK, plays a role in histone modification and G2/M cell cycle regulation. It is a 783 amino acid protein that contains one UBA domain and belongs to the Ser/Thr protein kinase family (AMPK subfamily). Localized to both the nucleus and the cytoplasm, SIK1 is a class II HDAC kinase that uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation.Synonyms: SIK, SIK-1, SNF1LK, Salt-inducible protein kinase 1, Serine/threonine-protein kinase SIK1, Serine/threonine-protein kinase SNF1-like kinase 1

ID gène: 150094

NCBI Accession: NP_775490

UniProt: P57059

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process