SIK1 anticorps (Center)
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- Antigène Voir toutes SIK1 Anticorps
- SIK1 (Salt-Inducible Kinase 1 (SIK1))
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Épitope
- Center
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SIK1 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects SIK1 at Center. Two isoforms of SIK1 are known to exist, this antibody will detect both isoforms. SIK1 antibody is predicted to not cross-react with other SIK protein family members.
- Réactivité croisée (Details)
- Species reactivity (tested):Human
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- 18 amino acid peptide near the center of human SIK1
- Top Product
- Discover our top product SIK1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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CISD2 associated with proliferation indicates negative prognosis in patients with hepatocellular carcinoma." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 10, pp. 13725-38, (2016) (PubMed).
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CISD2 associated with proliferation indicates negative prognosis in patients with hepatocellular carcinoma." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 10, pp. 13725-38, (2016) (PubMed).
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- Antigène
- SIK1 (Salt-Inducible Kinase 1 (SIK1))
- Autre désignation
- SIK1 (SIK1 Produits)
- Synonymes
- anticorps Msk, anticorps Sik, anticorps Snf1lk, anticorps SIK2, anticorps SNF1LK, anticorps MSK, anticorps SIK, anticorps salt-inducible kinase 1, anticorps salt inducible kinase 1, anticorps SIK1, anticorps Sik1
- Sujet
- Salt-inducible kinase 1 (SIK1), also known as SNF1LK or MSK, plays a role in histone modification and G2/M cell cycle regulation. It is a 783 amino acid protein that contains one UBA domain and belongs to the Ser/Thr protein kinase family (AMPK subfamily). Localized to both the nucleus and the cytoplasm, SIK1 is a class II HDAC kinase that uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation.Synonyms: SIK, SIK-1, SNF1LK, Salt-inducible protein kinase 1, Serine/threonine-protein kinase SIK1, Serine/threonine-protein kinase SNF1-like kinase 1
- ID gène
- 150094
- NCBI Accession
- NP_775490
- UniProt
- P57059
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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