ANAPC10 anticorps (Center)

N° du produit ABIN783594

Cet anticorps anti-ANAPC10 est un anticorps Lapin Polyclonal détectant ANAPC10 dans WB et EIA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour ANAPC10 anticorps (Center) (ABIN783594)

Antigène: ANAPC10 (Anaphase Promoting Complex Subunit 10 (ANAPC10))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANAPC10 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-ANAPC10 anticorps

Épitope: Center

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid peptide near the center of human APC10

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur ANAPC10

Antigène: ANAPC10 (Anaphase Promoting Complex Subunit 10 (ANAPC10))

Autre désignation: APC10 / ANAPC10

Sujet: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC10 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. It has been suggested that APC10 plays a role to regulate the binding of specific substrates to the APC/C complex, similar to that of coactivators.Synonyms: Anaphase-promoting complex subunit 10, Cyclosome subunit 10

ID gène: 10393

NCBI Accession: NP_055700

UniProt: Q9UM13

Pathways: M Phase