NLRX1 anticorps (N-Term)
Aperçu rapide pour NLRX1 anticorps (N-Term) (ABIN783701)
Antigène
Voir toutes NLRX1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody detects NLRX1 / NOD9 at N-term.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 14 amino acid peptide near the amino terminus of human NOD5
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- NLRX1 (NLR Family Member X1 (NLRX1))
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Autre désignation
- NLRX1 / NOD9
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Sujet
- NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-kB and JNK pathways by inducing reactive oxygen species production.Synonyms: Caterpiller 11.3, NLR family member X1, NOD26, NOD5, Nucleotide-binding oligomerization domain protein 26, Nucleotide-binding oligomerization domain protein 5, Nucleotide-binding oligomerization domain protein 9
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ID gène
- 79671
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NCBI Accession
- NP_078894
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UniProt
- Q86UT6
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Pathways
- SARS-CoV-2 Protein Interactome
Antigène
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