Axin anticorps (C-Term)

N° du produit ABIN783749

L’anticorps Lapin Polyclonal anti-Axin a été validé pour WB et EIA. Il convient pour détecter Axin dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Axin anticorps (C-Term) (ABIN783749)

Antigène: Axin (AXIN1) (Axin 1 (AXIN1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Axin est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Axin anticorps

Épitope: C-Term

Specificité: This antibody detects Axin-1 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 14 amino acid peptide near the carboxy terminus of human AXIN1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: 14 amino acid peptide near the carboxy terminus of human AXIN1

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur Axin

Antigène: Axin (AXIN1) (Axin 1 (AXIN1))

Autre désignation: Axin-1

Sujet: AXIN1 is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain and is thought to function as a negative regulator of the WNT signaling pathway that regulates embryonic axis formation. AXIN1 interacts with adenomatosis polyposis coli (APC), b-catenin, glycogen synthase kinase 3 beta, forming a tetrameric complex resulting in the regulation of the stabilization of b-catenin. Mutations in the AXIN1 gene have been associated various carcinomas, indicating that it also functions as a tumor suppressor.Synonyms: AXIN, AXIN1, Axis inhibition protein 1

ID gène: 8312

NCBI Accession: NP_003493

UniProt: O15169

Pathways: Signalisation WNT, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling