p300 anticorps (pSer1834) (FITC)

N° du produit ABIN800620

Cet anticorps Lapin Polyclonal détecte spécifiquement p300 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain, Souris et Poisson zèbre (Danio rerio).

Aperçu rapide pour p300 anticorps (pSer1834) (FITC) (ABIN800620)

Antigène: p300 (EP300) (E1A Binding Protein P300 (EP300))

Reactivité: Humain, Souris, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp p300 est conjugé à/à la FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-p300 anticorps (FITC)

Épitope: pSer1834

Réactivité croisée: Humain, Souris, Poisson zèbre (Danio rerio)

Homologie: Rat,Dog,Cow,Pig,Horse,Chicken,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Ep300 around the phosphorylation site of Ser1834

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur p300

Antigène: p300 (EP300) (E1A Binding Protein P300 (EP300))

Autre désignation: Ep300

Sujet:

Synonyms: CREBBP/EP300 inhibitory protein 1, Cyclic AMP responsive enhancer binding protein, E1A associated protein p300, E1A binding protein p300, EC 2.3.1.48, EP300, EP300: E1A binding protein p300, RB and P300 binding protein EID 1, Histone acetyltransferase p300, p300 HAT, Retinoblastoma protein associated protein.

Background: KAT3B/p300 is a transcriptional adapter protein (300 kDa)which is characterized by three cysteine and histidine rich regions and its C-terminus specifically binds the adenovirus E1A protein. KAT3B and associated proteins are components of TATA-binding protein (TBP)complexes. Protein kinase A mediated CREB phosphorylation results in the binding of CREB to a 265 kDa nuclear protein designated KAT3A/CBP(for CREB-binding protein). KAT3B and KAT3A are homologous to each other.

ID gène: 2033

Pathways: Signalisation p53, Signalisation Notch, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size