IRS2 anticorps (pSer731)

N° du produit ABIN801468

Cet anticorps anti-IRS2 est un anticorps Lapin Polyclonal détectant IRS2 dans FACS et IF (cc). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour IRS2 anticorps (pSer731) (ABIN801468)

Antigène: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRS2 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-IRS2 anticorps

Épitope: pSer731

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human IRS-2 around the phosphorylation site of Ser731

Isotype: IgG

Information d'application

Indications d'application: WB: (1:100-1000), IHC-P: (1:100-500), IF(IHC-P): (1:50-200)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur IRS2

Antigène: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Autre désignation: Irs-2

Sujet:

Synonyms: Insulin Receptor Substrate 2, IRS 2, IRS2.

Background: The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions, however, the distinct physiological roles of each IRS are unclear. Summary: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.

ID gène: 8660

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process