IGF1R anticorps (pTyr1165, pTyr1166)

N° du produit ABIN802233

Cet anticorps anti-IGF1R Polyclonal Lapin (ABIN802233) détecte spécifiquement IGF1R dans ELISA et FACS. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour IGF1R anticorps (pTyr1165, pTyr1166) (ABIN802233)

Antigène: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGF1R est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Détail du produit anti-IGF1R anticorps

Épitope: pTyr1165, pTyr1166

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human IGF1R around the phosphorylation site of Tyr1165+Tyr1166

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur IGF1R

Antigène: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Autre désignation: IGF1R +

Sujet:

Synonyms: IGF-1R Tyr1165/Tyr1166, IGF1R phospho Y1165+Y1166, IGF1R phospho Tyr1165+Tyr1166, p-IGF1R Tyr1165+Tyr1166, CD221, CD221 antigen, IGF 1 receptor, IGF 1R, IGF I receptor, IGF1R, IGFIR, IGFIRC, Insulin like growth factor 1 receptor, Insulin like growth factor 1 receptor precursor, JTK13, MGC142170, MGC142172, IGF1 Receptor, IGF1R_HUMAN.

Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008].

ID gène: 3480

UniProt: P08069

Pathways: Signalisation RTK, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy