APOB anticorps

N° du produit ABIN865414

Cet anticorps Souris Monoclonal détecte spécifiquement APOB dans WB, IHC, ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour APOB anticorps (ABIN865414)

Antigène: APOB (Apolipoprotein B (APOB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp APOB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 6G6

Détail du produit anti-APOB anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human ApoB expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FC: 1/200 - 1/400 ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100g/100l

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur APOB

Antigène: APOB (Apolipoprotein B (APOB))

Autre désignation: ApoB

Sujet: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. Synonyms: FLDB, LDLCQ4

Poids moléculaire: 516kDa

ID gène: 338

Pathways: Lipid Metabolism