Aurora A anticorps
Aperçu rapide pour Aurora A anticorps (ABIN865471)
Antigène
Voir toutes Aurora A (AURKA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Ascitic fluid
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Immunogène
- Purified recombinant fragment of human AURKA expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
- WB: 1/500 - 1/2000, IHC: 1/200-1/1000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 100g/100l
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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Autre désignation
- AURKA
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Sujet
- Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment. Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines. Synonyms: AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, AURORA2, MGC34538, AURKA
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Poids moléculaire
- 48kDa
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ID gène
- 6790
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Pathways
- Cycle Cellulaire, Asymmetric Protein Localization
Antigène
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