Glucagon anticorps

N° du produit ABIN865480

Cet anticorps Souris Monoclonal détecte spécifiquement Glucagon dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Glucagon anticorps (ABIN865480)

Antigène: Glucagon (GCG)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Glucagon est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 2F9

Détail du produit anti-Glucagon anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human GCG expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100g/100l

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur Glucagon

Antigène: Glucagon (GCG)

Autre désignation: GCG

Sujet: The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. Tissue specificity: Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP1 and GLP2 are also secreted in selected neurons in the brain. Synonyms: GLP1, GLP2, GRPP, GCG

Poids moléculaire: 21kDa

ID gène: 2641

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling