CDKN1C anticorps
Aperçu rapide pour CDKN1C anticorps (ABIN865500)
Antigène
Voir toutes CDKN1C AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Ascitic fluid
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Immunogène
- Purified recombinant fragment of human CDKN1C expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
- WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 100g/100l
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
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Autre désignation
- CDKN1C
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Sujet
- The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. Tissue specificity: Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver. Synonyms: BWS, WBS, p57, BWCR, KIP2, CDKN1C
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Poids moléculaire
- 57kDa
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ID gène
- 1028
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Pathways
- Cycle Cellulaire, Dopaminergic Neurogenesis
Antigène
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