PERK anticorps

N° du produit ABIN865515

Cet anticorps anti-PERK Monoclonal Souris (Clone 5G5) (ABIN865515) détecte spécifiquement PERK dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PERK anticorps (ABIN865515)

Antigène: PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PERK est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 5G5

Détail du produit anti-PERK anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human EIF2AK3 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100g/100l

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur PERK

Antigène: PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))

Autre désignation: EIF2AK3

Sujet: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. Synonyms: PAX8

Poids moléculaire: 125kDa

ID gène: 9451

Pathways: Hormone Transport, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response