CD86 anticorps

N° du produit ABIN865523

L’anticorps anti-CD86 Monoclonal Souris est utilisé pour la détection de CD86 dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour CD86 anticorps (ABIN865523)

Antigène: CD86

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD86 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 1B3

Détail du produit anti-CD86 anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human EIF2AK3 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100g/100l

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur CD86

Antigène: CD86

Autre désignation: CD86

Sujet: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. Tissue specificity: Expressed by activated B-lymphocytes and monocytes. Synonyms: B70, B7-2, LAB72, CD28LG2, MGC34413, CD86

Poids moléculaire: 52kDa

ID gène: 942

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation