CD44 anticorps (AA 734-738)

N° du produit ABIN871672

Cet anticorps Lapin Polyclonal détecte spécifiquement CD44 dans WB. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour CD44 anticorps (AA 734-738) (ABIN871672)

Antigène: CD44

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD44 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD44 anticorps

Épitope: AA 734-738

Specificité: The antibody detects endogenous level of total CD44 protein.

Purification: Affinity purified

Immunogène: Peptide sequence around AA 734-738 (Q-N-V-D-M) derived from Human CD44. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Information d'application

Indications d'application: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur CD44

Antigène: CD44

Autre désignation: CD44

Sujet: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

Poids moléculaire: 80 kDa

ID gène: 960

NCBI Accession: NP_000601

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling