PPM1F anticorps (AA 325-425)
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- Antigène Voir toutes PPM1F Anticorps
- PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
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Épitope
- AA 325-425
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PPM1F est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human PPM1F
- Isotype
- IgG
- Top Product
- Discover our top product PPM1F Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
- Autre désignation
- PPM1F (PPM1F Produits)
- Synonymes
- anticorps 1110021B16Rik, anticorps 4933427B07Rik, anticorps CaMKPase, anticorps Popx2, anticorps mKIAA0015, anticorps CAMKP, anticorps FEM-2, anticorps POPX2, anticorps hFEM-2, anticorps protein phosphatase, Mg2+/Mn2+ dependent 1F, anticorps protein phosphatase 1F (PP2C domain containing), anticorps protein phosphatase, Mg2+/Mn2+ dependent, 1F, anticorps PPM1F, anticorps Ppm1f
- Sujet
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Synonyms: Ca2+/calmodulin-dependent protein kinase phosphatase, CaM-kinase phosphatase,CaMKPase, hFEM-2, KIAA0015, Partner of PIX 2, POPX2, Protein phosphatase 1F, PPM1F_HUMAN.
Background: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008].
- ID gène
- 9647
- Pathways
- Positive Regulation of Endopeptidase Activity
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