APOB anticorps (AbBy Fluor® 350)

N° du produit ABIN883109

L’anticorps Lapin Polyclonal anti-APOB a été validé pour WB. Il convient pour détecter APOB dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour APOB anticorps (AbBy Fluor® 350) (ABIN883109)

Antigène: APOB (Apolipoprotein B (APOB))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APOB est conjugé à/à la AbBy Fluor® 350

Application: Western Blotting (WB)

Détail du produit anti-APOB anticorps (AbBy Fluor® 350)

Homologie: Human,Mouse,Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Apolipoprotein B

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur APOB

Antigène: APOB (Apolipoprotein B (APOB))

Autre désignation: Apolipoprotein B

Sujet:

Synonyms: Apo B 100, Apo B, Apo B-100, Apo B-48, ApoB 100, ApoB 48, ApoB, APOB protein, APOB_HUMAN, Apolipoprotein B 100, Apolipoprotein B 48, Apolipoprotein B, Apolipoprotein B-48, FLDB.

Background: Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.Involvement in disease: Defects in APOB are a cause of hypobetalipoproteinemia familial type 1 (FHBL1) . A disorder characterized by highly reduced plasma concentrations of low density lipoproteins, and dietary fat malabsorption. Clinical presentation may vary from no symptoms to severe gastrointestinal and neurological dysfunction similar to abetalipoproteinemia.Defects in APOB are a cause of familial ligand-defective apolipoprotein B-100 (FDB). FDB is a dominantly inherited disorder of lipoprotein metabolism leading to hypercholesterolemia and increased proneness to coronary artery disease (CAD). The plasma cholesterol levels are dramatically elevated due to impaired clearance of LDL particles by defective APOB/E receptors.

ID gène: 338

Pathways: Lipid Metabolism