CCDC98 anticorps (AA 51-150) (AbBy Fluor® 488)

N° du produit ABIN888405

Cet anticorps anti-CCDC98 Polyclonal Lapin conjugué à AbBy Fluor® 488 (ABIN888405) détecte spécifiquement CCDC98 dans WB, IF (cc) et IF (p). L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour CCDC98 anticorps (AA 51-150) (AbBy Fluor® 488) (ABIN888405)

Antigène: CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCDC98 est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-CCDC98 anticorps (AbBy Fluor® 488)

Épitope: AA 51-150

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CCDC98

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CCDC98

Antigène: CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))

Autre désignation: CCDC98

Sujet:

Synonyms: ABRA1, CCDC98, BRCA1-A complex subunit Abraxas, Coiled-coil domain-containing protein 98, Protein FAM175A, FAM175A, UNQ496/PRO1013

Background: Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.

ID gène: 84142

UniProt: Q6UWZ7

Pathways: Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus