C3 anticorps (AbBy Fluor® 488)

N° du produit ABIN901513

Cet anticorps Chèvre Polyclonal détecte spécifiquement C3 dans WB, IF (p) et IF (cc). Il présente une réactivité envers Souris.

Aperçu rapide pour C3 anticorps (AbBy Fluor® 488) (ABIN901513)

Antigène: C3 (Complement Component 3 (C3))

Reactivité: Souris

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp C3 est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-C3 anticorps (AbBy Fluor® 488)

Réactivité croisée: Souris

Homologie: Human

Purification: Purified by Protein A.

Immunogène: human Complement C3 purified from human plasma

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur C3

Antigène: C3 (Complement Component 3 (C3))

Autre désignation: Complement C3

Sujet:

Synonyms: Acylation stimulating protein cleavage product, Acylation-stimulating protein cleavage product, AHUS5, ARMD9, ASP, ASP, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 antibody C3 antibody C3a anaphylatoxin, CO3_HUMAN, Complement C3 alpha chain, Complement C3, Complement C3 beta chain, Complement C3 precursor, Complement C3b alpha chain, Complement C3c alpha' chain fragment 2, Complement C3c fragment, Complement C3d fragment, Complement C3f fragment, Complement C3g fragment, Complement component 3, Complement component 3 precursor, Complement component C3, Complement factor 3, CPAMD1, Plp.

Background: The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.

ID gène: 718

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling