PRUNE anticorps (AA 201-300) (AbBy Fluor® 488)

N° du produit ABIN912355

Cet anticorps Lapin Polyclonal détecte spécifiquement PRUNE dans WB, IF (cc) et IF (p). Il présente une réactivité envers Souris.

Aperçu rapide pour PRUNE anticorps (AA 201-300) (AbBy Fluor® 488) (ABIN912355)

Antigène: PRUNE (Prune Exopolyphosphatase (PRUNE))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRUNE est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-PRUNE anticorps (AbBy Fluor® 488)

Épitope: AA 201-300

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DRES17

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PRUNE

Antigène: PRUNE (Prune Exopolyphosphatase (PRUNE))

Autre désignation: DRES17

Sujet:

Synonyms: DRES17, Drosophila-related expressed sequence 17, hprune, HTCD37, Prune homolog, PRUNE like protein, TcD37 homolog, PRUNE_HUMAN.

Background: PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune, h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness.

ID gène: 58497