FAS anticorps (FITC)

N° du produit ABIN920646

Cet anticorps anti-FAS est un anticorps Souris Monoclonal détectant FAS dans FACS et IHC. Adapté pour Humain.

Aperçu rapide pour FAS anticorps (FITC) (ABIN920646)

Antigène: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FAS est conjugé à/à la FITC

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC)

Clone: APO-1-1

Détail du produit anti-FAS anticorps (FITC)

Specificité: Reacts specifically with the human Fas antigen, although the epitope has not been mapped. Binds both the soluble and membrane-bound forms of Fas. Does not react with mouse or gibbon Fas. Recognizes activated T-cells and a subpopulation of B-cells. The cell-surface Fas antigen is a 48 kDa transmembrane protein that can mediate apoptosis/programmed cell death and belongs to the nerve growth factor (NGF)/tumor necrosis factor (TNF) receptor superfamily. The human Fas antigen is expressed in various human cells, including activated peripheral T and B lymphocytes, Various tumor cell lines, leukemic T cells, and myeloid cells. It is also differentially expressed on human thymocytes during thymic maturation.

Attributs du produit: Mouse myeloma (P3.X63.Ag8.653) x immunized mouse (Balb/c) spleen cells.

Purification: Purified by protein A chromatography

Pureté: > 95 % by SDS-PAGE.

Immunogène: Human B lymphoblast cell line SKW6.4 cell surface molecules

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry on cryostat sections and on cytospin preparations. Not suitable for use on paraffin sections. Flow Cytometry: Use at 1:20 dilution (as determined on SKW6.4 cells.

Restrictions: For Research Use only

Stockage

Buffer: FITC-labeled antibody in 1 ml PBS, pH 7.4 with 1% BSA and 0.02% NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur FAS

Antigène: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Autre désignation: Fas

Sujet: Monoclonal antibody recognizing Fas protein, FITC-labeled for simplified flow cytometry procedures. Clone Apo-1-1 is an IgG1 isotype switch variant of the IgG3 clone APO-1-3 (Cat. No. MC-095).

Pathways: Signalisation p53, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity