ACTN2 anticorps (C-Term)

N° du produit ABIN925860

Cet anticorps anti-ACTN2 est un anticorps Lapin Polyclonal détectant ACTN2 dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Poulet et Xenopus laevis.

Aperçu rapide pour ACTN2 anticorps (C-Term) (ABIN925860)

Antigène: ACTN2 (Actinin, alpha 2 (ACTN2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Poulet, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACTN2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ACTN2 anticorps

Épitope: C-Term

Réactivité croisée: Rat (Rattus), Humain, Boeuf (Vache), Chien, Poulet, Poisson zebré (Brachydanio rerio), Grenouille

Immunogène: ACTN2 antibody was raised in rabbit using the C terminal of ACTN2 as the immunogen

Information d'application

Indications d'application: WB: 0.625 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

ACTN2 Blocking Peptide, (ABIN939512), is also available for use as a blocking control in assays to test for specificity of this ACTN2 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur ACTN2

Antigène: ACTN2 (Actinin, alpha 2 (ACTN2))

Autre désignation: ACTN2

Sujet: The alpha-actinins are a multigene family of four actin-binding proteins related to dystrophin. The two skeletal muscle isoforms of alpha-actinin (ACTN2 and ACTN3) are major structural components of the Z-line involved in anchoring the actin-containing thin filaments. In humans, ACTN2 is expressed in all muscle fibres, while ACTN3 expression is restricted to a subset of type 2 fibres. Murine Actn2 and Actn3 are differentially expressed, spatially and temporally, during embryonic development and, in contrast to humans, alpha-actinin-2 expression does not completely overlap alpha-actinin-3 in postnatal skeletal muscle, suggesting independent function. Synonyms: Polyclonal ACTN2 antibody, Anti-ACTN2 antibody.

Pathways: Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity