ACTN2 anticorps (C-Term)

N° du produit ABIN925860

Détail du produit anti-ACTN2 anticorps

Antigène: ACTN2 (Actinin, alpha 2 (ACTN2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Poulet, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACTN2 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Rat (Rattus), Humain, Boeuf (Vache), Chien, Poulet, Poisson zebré (Brachydanio rerio), Grenouille

Immunogène: ACTN2 antibody was raised in rabbit using the C terminal of ACTN2 as the immunogen

Information d'application

Indications d'application: WB: 0.625 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

ACTN2 Blocking Peptide, catalog no. 33R-4126, is also available for use as a blocking control in assays to test for specificity of this ACTN2 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur ACTN2

Antigène: ACTN2 (Actinin, alpha 2 (ACTN2))

Autre désignation: ACTN2 (ACTN2 Produits)

Synonymes: anticorps MGC89234, anticorps ACTN2, anticorps 1110008F24Rik, anticorps CMD1AA, anticorps wu:fd44c03, anticorps zgc:123223, anticorps actinin alpha 2, anticorps actinin, alpha 2b, anticorps actinin alpha 2 S homeolog, anticorps actn2, anticorps ACTN2, anticorps Actn2, anticorps actn2b, anticorps actn2.S

Sujet: The alpha-actinins are a multigene family of four actin-binding proteins related to dystrophin. The two skeletal muscle isoforms of alpha-actinin (ACTN2 and ACTN3) are major structural components of the Z-line involved in anchoring the actin-containing thin filaments. In humans, ACTN2 is expressed in all muscle fibres, while ACTN3 expression is restricted to a subset of type 2 fibres. Murine Actn2 and Actn3 are differentially expressed, spatially and temporally, during embryonic development and, in contrast to humans, alpha-actinin-2 expression does not completely overlap alpha-actinin-3 in postnatal skeletal muscle, suggesting independent function. Synonyms: Polyclonal ACTN2 antibody, Anti-ACTN2 antibody.

Pathways: Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity