Caspase 3 anticorps (N-Term)

N° du produit ABIN925983

Cet anticorps anti-Caspase 3 est un anticorps Lapin Polyclonal détectant Caspase 3 dans WB et IHC. Adapté pour Humain, Rat, Boeuf (Vache), Chien, Lapin et Porc.

Aperçu rapide pour Caspase 3 anticorps (N-Term) (ABIN925983)

Antigène: Caspase 3 (CASP3)

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Caspase 3 anticorps

Épitope: N-Term

Réactivité croisée: Rat (Rattus), Porc, Chien, Lapin, Boeuf (Vache)

Immunogène: CASP3 antibody was raised in rabbit using the N terminal of CASP3 as the immunogen

Information d'application

Indications d'application: WB: 5 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

CASP3 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CASP3 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur Caspase 3

Antigène: Caspase 3 (CASP3)

Autre désignation: CASP3

Sujet: CASP3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. Synonyms: Polyclonal CASP3 antibody, Anti-CASP3 antibody, caspase 3, apoptosis-related cysteine peptidase antibody.

Pathways: Apoptose, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation