DIABLO anticorps (C-Term)

N° du produit ABIN925989

Détail du produit anti-DIABLO anticorps

Antigène: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Épitope: C-Term

Reactivité: Humain, Boeuf (Vache), Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DIABLO est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Chien, Porc, Boeuf (Vache)

Immunogène: DIABLO antibody was raised in rabbit using the C terminal of DIABLO as the immunogen

Information d'application

Indications d'application: WB: 0.3125 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

DIABLO Blocking Peptide, catalog no. 33R-5520, is also available for use as a blocking control in assays to test for specificity of this DIABLO antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur DIABLO

Antigène: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Autre désignation: DIABLO (DIABLO Produits)

Synonymes: anticorps smac, anticorps smac3, anticorps diablo-s, anticorps 0610041G12Rik, anticorps 1700006L01Rik, anticorps AU040403, anticorps Smac, anticorps DFNA64, anticorps SMAC, anticorps DBO, anticorps XSmac, anticorps diablo, IAP-binding mitochondrial protein, anticorps diablo IAP-binding mitochondrial protein, anticorps diablo, IAP-binding mitochondrial protein L homeolog, anticorps diablo, anticorps Diablo, anticorps DIABLO, anticorps diablo.L

Sujet: DIABLO is an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Several alternatively spliced transcript variants that encode distinct isoforms have been described for this gene but the validity of some transcripts, and their predicted ORFs, has not been determined conclusively. Synonyms: Polyclonal DIABLO antibody, Anti-DIABLO antibody, diablo homolog, Drosophila antibody.

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity