NAPA anticorps (N-Term)
Aperçu rapide pour NAPA anticorps (N-Term) (ABIN926040)
Antigène
Voir toutes NAPA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Réactivité croisée
- Souris, Rat (Rattus), Boeuf (Vache), Chien, Grenouille, Poisson zebré (Brachydanio rerio)
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Immunogène
- NAPA antibody was raised in rabbit using the N terminal of NAPA as the immunogen
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Indications d'application
- Optimal conditions should be determined by the investigator.
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Commentaires
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NAPA Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this NAPA antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))
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Autre désignation
- NAPA
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Sujet
- The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. Synonyms: Polyclonal NAPA antibody, Anti-NAPA antibody, N-ethylmaleimide-sensitive factor attachment protein, alpha antibody.
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Pathways
- Synaptic Vesicle Exocytosis, Asymmetric Protein Localization
Antigène
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