MAPKAP Kinase 3 anticorps (C-Term)
Aperçu rapide pour MAPKAP Kinase 3 anticorps (C-Term) (ABIN926459)
Antigène
Voir toutes MAPKAP Kinase 3 (MAPKAPK3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Purification
- Purified
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Immunogène
- MAPKAPK3 antibody was raised in rabbit using the C terminal of MAPKAPK3 as the immunogen
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Indications d'application
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
Commentaires
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MAPKAPK3 Blocking Peptide, (ABIN939713), is also available for use as a blocking control in assays to test for specificity of this MAPKAPK3 antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
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Autre désignation
- MAPKAPK3
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Sujet
- MAPKAPK3 is a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Synonyms: Polyclonal MAPKAPK3 antibody, Anti-MAPKAPK3 antibody, mitogen-activated protein kinase-activated protein kinase 3 antibody, 3PK antibody, MAPKAP3 antibody.
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Pathways
- Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
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