UBE2V1 anticorps (C-Term)

N° du produit ABIN926783

L’anticorps anti-UBE2V1 Polyclonal Lapin est utilisé pour la détection de UBE2V1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour UBE2V1 anticorps (C-Term) (ABIN926783)

Antigène: UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2V1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-UBE2V1 anticorps

Épitope: C-Term

Purification: Purified

Immunogène: UBE2 V1 antibody was raised in rabbit using the C terminal of UBE2 1 as the immunogen

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Commentaires:

UBE2V1 Blocking Peptide, (ABIN936320), is also available for use as a blocking control in assays to test for specificity of this UBE2V1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur UBE2V1

Antigène: UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

Autre désignation: UBE2V1

Sujet: Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Synonyms: Polyclonal UBE2V1 antibody, Anti-UBE2V1 antibody, ubiquitin-conjugating enzyme E2 variant 1 antibody, CIR1 antibody, CROC-1 antibody, CROC1 antibody, UBE2V antibody, UEV-1 antibody, UEV1 antibody, UEV1A antibody.

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades