IGF1R anticorps (Middle Region)
Aperçu rapide pour IGF1R anticorps (Middle Region) (ABIN926846)
Antigène
Voir toutes IGF1R AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Réactivité croisée
- Souris, Rat (Rattus), Porc, Boeuf (Vache), Poulet, Poisson zebré (Brachydanio rerio), Grenouille
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Purification
- Purified
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Immunogène
- IGF1 R antibody was raised in rabbit using the middle region of IGF1 as the immunogen
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Indications d'application
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
Commentaires
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IGF1R Blocking Peptide, (ABIN937530), is also available for use as a blocking control in assays to test for specificity of this IGF1R antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
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Autre désignation
- IGF1R
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Sujet
- This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Synonyms: Polyclonal IGF1R antibody, Anti-IGF1R antibody, insulin-like growth factor 1 receptor antibody, CD221 antibody, IGFIR antibody, JTK13 antibody, MGC142170 antibody, MGC142172 antibody, MGC18216 antibody.
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Pathways
- Signalisation RTK, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
Antigène
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