Cyclin D3 anticorps (C-Term)

N° du produit ABIN926905

Cet anticorps Lapin Polyclonal détecte spécifiquement Cyclin D3 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Porc et Poulet.

Aperçu rapide pour Cyclin D3 anticorps (C-Term) (ABIN926905)

Antigène: Cyclin D3 (CCND3)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin D3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Cyclin D3 anticorps

Épitope: C-Term

Réactivité croisée: Souris, Rat (Rattus), Chien, Boeuf (Vache), Porc, Poulet

Purification: Purified

Immunogène: CCND3 antibody was raised in rabbit using the C terminal of CCND3 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

CCND3 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CCND3 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur Cyclin D3

Antigène: Cyclin D3 (CCND3)

Autre désignation: CCND3

Sujet: CCND3 encodes a protein that belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Synonyms: Polyclonal CCND3 antibody, Anti-CCND3 antibody, cyclin D3 antibody.

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process