CDC25A anticorps (Middle Region)

N° du produit ABIN926907

Cet anticorps anti-CDC25A est un anticorps Lapin Polyclonal détectant CDC25A dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Poulet, Xenopus laevis et Poisson zèbre (Danio rerio).

Aperçu rapide pour CDC25A anticorps (Middle Region) (ABIN926907)

Antigène: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poulet, Xenopus laevis, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC25A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CDC25A anticorps

Épitope: Middle Region

Réactivité croisée: Souris, Rat (Rattus), Boeuf (Vache), Chien, Grenouille, Poisson zebré (Brachydanio rerio), Poulet

Purification: Purified

Immunogène: CDC25 A antibody was raised in rabbit using the middle region of CDC25 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

CDC25A Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CDC25A antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur CDC25A

Antigène: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Autre désignation: CDC25A

Sujet: CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. Synonyms: Polyclonal CDC25A antibody, Anti-CDC25A antibody, cell division cycle 25 homolog A, S. pombe antibody, CDC25A2 antibody.

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase