TYK2 anticorps (C-Term)

N° du produit ABIN927289

Détail du produit anti-TYK2 anticorps

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TYK2 est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: TYK2 antibody was raised in rabbit using the C terminal of TYK2 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur TYK2

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Autre désignation: TYK2 (TYK2 Produits)

Synonymes: anticorps JTK1, anticorps tyrosine kinase 2, anticorps TYK2, anticorps Tyk2

Sujet: This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. Synonyms: Polyclonal TYK2 antibody, Anti-TYK2 antibody, tyrosine kinase 2 antibody, JTK1 antibody.

Pathways: Signalistation JAK/STAT, Hepatitis C