TLE1 anticorps (N-Term)

N° du produit ABIN927372

Détail du produit anti-TLE1 anticorps

Antigène: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Épitope: N-Term

Reactivité: Humain, Poisson zèbre (Danio rerio), Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLE1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Poulet, Poisson zebré (Brachydanio rerio)

Purification: Purified

Immunogène: TLE1 antibody was raised in rabbit using the N terminal of TLE1 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

TLE1 Blocking Peptide, catalog no. 33R-8077, is also available for use as a blocking control in assays to test for specificity of this TLE1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur TLE1

Antigène: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Autre désignation: TLE1 (TLE1 Produits)

Synonymes: anticorps ESG, anticorps ESG1, anticorps GRG1, anticorps C230057C06Rik, anticorps Estm14, anticorps Grg1, anticorps Tle4l, anticorps TLE1, anticorps transducin like enhancer of split 1, anticorps transducin-like enhancer protein 1, anticorps transducin-like enhancer of split 1, anticorps transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila), anticorps TLE1, anticorps Smp_150080, anticorps Tle1, anticorps LOC100354911, anticorps LOC100524475, anticorps LOC100061341

Sujet: TLE1 is a transcriptional corepressor that binds to a number of transcription factors. TLE1 inhibits NF-kappa-B-regulated gene expression and the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. TLE1 has an unusual function as coactivator for ESRRG. Synonyms: Polyclonal TLE1 antibody, Anti-TLE1 antibody, transducin-like enhancer of split 1, E, sp1 homolog, Drosophila antibody, ESG antibody, ESG1 antibody, GRG1 antibody.

Pathways: Signalisation WNT, SARS-CoV-2 Protein Interactome