TANK anticorps (C-Term)

N° du produit ABIN927714

Détail du produit anti-TANK anticorps

Antigène: TANK (TRAF Family Member-Associated NFKB Activator (TANK))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TANK est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: TANK antibody was raised in rabbit using the C terminal of TANK as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

TANK Blocking Peptide, catalog no. 33R-4584, is also available for use as a blocking control in assays to test for specificity of this TANK antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur TANK

Antigène: TANK (TRAF Family Member-Associated NFKB Activator (TANK))

Autre désignation: TANK (TANK Produits)

Synonymes: anticorps I-TRAF, anticorps ITRAF, anticorps TRAF2, anticorps C86182, anticorps E430026L09Rik, anticorps zgc:153048, anticorps i-traf, anticorps tank, anticorps traf2, anticorps TRAF family member associated NFKB activator, anticorps TRAF family member-associated Nf-kappa B activator, anticorps TRAF family member-associated NFKB activator, anticorps TRAF family member associated NFKB activator L homeolog, anticorps TANK, anticorps Tank, anticorps tank, anticorps tank.L

Sujet: The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, TANK can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation.The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. Synonyms: Polyclonal TANK antibody, Anti-TANK antibody, TRAF family member-associated NFKB activator antibody.

Pathways: Signalisation p53, Signalisation TLR, Activation of Innate immune Response